The HPE ProLiant DL380 Gen10 Server, Part Number P06421-B21, is a versatile and reliable 2U rack server designed to support a wide range of business and enterprise workloads. Built on the HPE ProLiant Gen10 platform, this server delivers a balanced combination of performance, scalability, storage flexibility, and enterprise-class reliability, making it suitable for growing businesses, data centers, virtualization environments, and general-purpose IT infrastructure.
This configuration is powered by an Intel Xeon Silver 4114 processor featuring 10 cores and a base clock speed of 2.2GHz. The server comes with 32GB of HPE DDR4 memory, providing a strong foundation for demanding applications and multitasking workloads. The DL380 Gen10 platform supports additional memory expansion, allowing organizations to scale their infrastructure as business requirements grow.
The P06421-B21 configuration features an 8SFF (Small Form Factor) chassis, supporting up to eight 2.5-inch storage drives in the front configuration. This provides flexibility for organizations that require a combination of performance and storage density. Depending on the system configuration and compatible hardware, the platform can support various storage technologies, including SAS, SATA, and other supported enterprise storage options.
For storage management and data protection, the server includes an HPE Smart Array P408i-a storage controller. This enterprise-class controller helps manage connected storage devices and supports RAID configurations, providing improved data availability, performance, and storage management capabilities.
The HPE ProLiant DL380 Gen10 is designed for scalability and future expansion. Its 2U rack form factor provides space for additional hardware, including compatible memory modules, storage devices, PCIe expansion cards, networking adapters, and other enterprise components. This flexibility makes the server suitable for businesses that require an infrastructure platform capable of adapting to changing workload requirements.
The server is equipped with an 800W HPE Flex Slot Platinum hot-plug power supply, designed to provide efficient and reliable power delivery. The hot-plug design also supports easier maintenance and helps reduce downtime during service or power supply replacement.
HPE ProLiant Gen10 servers also provide advanced system management capabilities through HPE iLO 5 technology. Integrated Lights-Out enables administrators to remotely monitor and manage the server, helping simplify system administration, troubleshooting, deployment, and maintenance. This makes the DL380 Gen10 an excellent choice for organizations managing servers in remote locations or data center environments.
With its powerful Intel Xeon processor, expandable DDR4 memory, flexible 8SFF storage configuration, HPE Smart Array RAID controller, enterprise-grade management capabilities, and 2U rack design, the HPE ProLiant DL380 Gen10 P06421-B21 provides a dependable platform for a variety of IT workloads.
The HPE ProLiant DL380 Gen10 P06421-B21 is well suited for virtualization, business applications, databases, file and print services, cloud environments, enterprise infrastructure, and general-purpose computing. Its combination of performance, expandability, and reliability makes it an excellent solution for organizations looking for a scalable and efficient rack server platform.
| Configuration | Details |
|---|---|
| Part Number | P06421-B21 |
| Brand | HPE |
| Series | ProLiant |
| Model | DL380 Gen10 |
| Form Factor | 2U Rack Server |
| Processor | Intel Xeon Silver 4114 |
| CPU Cores | 10-Core |
| CPU Speed | 2.20 GHz |
| Processor Quantity | 1 Processor |
| Memory | 32GB DDR4 Registered Memory |
| RAID Controller | HPE Smart Array P408i-a |
| Drive Bay Configuration | 8SFF |
| Drive Bay Size | 2.5-inch |
| Hard Drives Included | No Hard Drives Included |
| Hard Drive Brand | N/A – Drives Not Included |
| Power Supply | 800W |
| Server Management | HPE iLO 5 |
| Configuration Type | Pre-configured Performance Server |





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