HPE ProLiant ML110 Gen10 4LFF Hot Plug CTO Tower Server – 872307-B21

Product Overview

The HPE ProLiant ML110 Gen10 4LFF Configure-to-Order Server – 872307-B21 is a single-socket 4.5U tower server designed for small and medium-sized businesses, remote and branch offices, and enterprise workloads that require a balance of performance, expandability, storage capacity, and manageability.

The ML110 Gen10 supports Intel Xeon Scalable processors, DDR4 Registered DIMM memory, PCIe 3.0 expansion, enterprise RAID options, hot-plug LFF storage, and HPE iLO 5 remote management. The 872307-B21 specifically provides a 4 × LFF hot-plug drive configuration.

Because 872307-B21 is a CTO SKU, the processor, memory, storage drives, RAID controller, and power-supply configuration can be selected according to the customer’s requirements. The processor is not included as standard, and HPE specifies that hard drives do not ship standard with the base configuration

The HPE ProLiant ML110 Gen10 is a single-processor server using the Intel C621 platform. It supports both 1st-generation and 2nd-generation Intel Xeon Scalable processors, depending on the supported configuration. HPE lists processors from the Xeon Bronze, Silver, and Gold families.

Examples include:

Intel Xeon Bronze

• Xeon Bronze 3104 — 6 cores
• Xeon Bronze 3106 — 8 cores
• Xeon Bronze 3204 — 6 cores
• Xeon Bronze 3206R — 8 cores

Intel Xeon Silver

• Xeon Silver 4108 — 8 cores
• Xeon Silver 4110 — 8 cores
• Xeon Silver 4112 — 4 cores
• Xeon Silver 4208 — 8 cores
• Xeon Silver 4210 — 10 cores
• Xeon Silver 4210R — 10 cores
• Xeon Silver 4214 — 12 cores
• Xeon Silver 4214R — 12 cores
• Xeon Silver 4215 — 8 cores
• Xeon Silver 4216 — 16 cores

Intel Xeon Gold

• Xeon Gold 5120 — 14 cores
• Xeon Gold 5122 — 4 cores
• Xeon Gold 5215 — 10 cores
• Xeon Gold 5218N — 16 cores
• Xeon Gold 5222 — 4 cores

HPE specifies processor support up to 16 cores on this platform, depending on the selected processor.

Website Listing

Since 872307-B21 is a CTO chassis, do not assign a specific CPU unless you know what is installed in your actual unit.

Processor: Not Included – Configurable

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Memory

The ML110 Gen10 provides 6 DDR4 DIMM slots, with six memory channels available for the single processor.

It supports HPE SmartMemory DDR4 Registered DIMMs (RDIMM) and can support up to 192GB of RDIMM memory, using 6 × 32GB RDIMMs. Depending on the processor and memory configuration, supported memory speeds can reach up to 2933 MT/s.

Important: HPE states that LRDIMMs are not qualified for this server, and RDIMM and LRDIMM types should not be mixed.

Website Listing

Memory: Not Included – Configurable
Memory Type: DDR4 ECC Registered DIMM (RDIMM)
DIMM Slots: 6
Maximum: Up to 192GB

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Storage – 4LFF Hot Plug

The main feature of 872307-B21 is the 4LFF Hot Plug drive cage.

LFF = Large Form Factor, referring to the 3.5-inch drive format.

The server includes:

4 × 3.5-inch LFF Hot Plug bays

These bays support compatible SAS and SATA HDD/SSD configurations. HPE also states that the 4LFF configuration can be upgraded to 8 LFF hot-plug bays with the appropriate additional drive cage configuration.

Supported storage options include:

• 3.5-inch SAS HDD
• 3.5-inch SATA HDD
• 3.5-inch SAS SSD
• 3.5-inch SATA SSD

HPE states that hard drives do not ship standard with the CTO server.

Website Listing

Drive Bays: 4 × LFF Hot Plug
Storage: No Drives Included – Configurable

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Maximum Storage Capacity

Depending on the installed drive cage and drives, the ML110 Gen10 platform supports substantial internal storage.

HPE lists configurations including:

• Up to 160TB with 8 × 20TB Hot Plug LFF SAS HDD
• Up to 160TB with 8 × 20TB Hot Plug LFF SATA HDD
• Up to 61.44TB with 8 × 7.68TB LFF SAS SSD
• Up to 61.44TB with 8 × 7.68TB LFF SATA SSD

These maximum figures apply to the broader ML110 Gen10 platform when the 4LFF configuration is expanded to 8LFF.

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RAID & Storage Controller

The ML110 Gen10 provides the HPE Smart Array S100i SR Gen10 Software RAID as an embedded storage option.

The S100i supports:

• RAID 0
• RAID 1
• RAID 5
• RAID 10

HPE specifies that the S100i supports the embedded SATA ports and provides 10 SATA ports, with two ports leveraged for the M.2 option.

For customers requiring hardware RAID, optional controllers include:

• HPE Smart Array E208i-p SR Gen10
• HPE Smart Array E208e-p SR Gen10
• HPE Smart Array P408i-p SR Gen10
• HPE Smart Array P408e-p SR Gen10

The P408-series controllers are the performance-oriented options, while the E208-series controllers are positioned as essential RAID solutions.

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Network Connectivity

The server includes an embedded:

HPE Ethernet 1Gb 2-port 332i Adapter

This provides 2 × 1GbE RJ-45 network ports as standard. HPE’s QuickSpecs confirms the 332i adapter as the embedded network controller for the ML110 Gen10 CTO configurations.

Additional networking can be added through the available PCIe expansion slots.

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PCIe Expansion

The ML110 Gen10 provides 5 × PCIe 3.0 expansion slots.

The slots provide different electrical configurations, including x16, x8, and x4 connections. HPE lists full-height expansion capability, with one slot supporting a full-height, full-length card and another supporting cards up to approximately 9.5 inches.

This allows the server to be expanded with:

• RAID controllers
• Network adapters
• Fibre Channel adapters
• Storage controllers
• GPU/accelerator options
• Other PCIe expansion cards

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HPE iLO 5 Management

The ML110 Gen10 includes HPE Integrated Lights-Out (iLO) 5 for remote server management.

iLO provides capabilities such as:

• Remote monitoring
• Hardware health monitoring
• Remote console
• Remote configuration
• Server troubleshooting
• Firmware management
• Remote OS deployment

HPE also provides Intelligent Provisioning, simplifying server setup and operating-system deployment.

The server also supports HPE OneView Standard, while enhanced iLO capabilities can be enabled with optional licenses.

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Power Supply Options

The ML110 Gen10 supports several power-supply configurations.

HPE lists:

• 350W ATX Power Supply
• 550W ATX Power Supply
• 500W Flex Slot Platinum Hot Plug
• 800W Flex Slot Platinum Hot Plug
• 800W Flex Slot Titanium Hot Plug

The Flex Slot power supplies provide higher-efficiency options and can support redundant power configurations when the appropriate RPS enablement kit is installed.

Website Listing

For a CTO listing, I recommend:

Power Supply: Not Included / Configurable

unless you have verified the actual PSU installed in your refurbished unit.

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Cooling

The standard ML110 Gen10 platform uses:

• 1 × system fan
• 1 × PCIe fan

HPE also offers a redundant fan kit for configurations requiring additional cooling and redundancy. Certain high-performance storage configurations, including SAS SSDs and certain 15K RPM SAS HDD configurations, require the redundant fan configuration.

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Tower Form Factor

The ML110 Gen10 is a 4.5U tower server, rather than a standard rack server.

HPE describes the ML110 Gen10 as a single-processor tower platform designed for SMB and remote/branch-office environments while still providing enterprise-class reliability, manageability, and expandability.

An optional sliding shelf can be used when rack installation is required.

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Interfaces & Connectivity

The server provides:

• 2 × RJ-45 1GbE
• 1 × VGA
• 1 × iLO Management Port
• 1 × iLO Service Port
• 2 × front USB 3.0
• 2 × rear USB 3.0
• 1 × internal USB 3.0
• 2 × rear USB 2.0
• 1 × internal USB 2.0
• Optional serial port
• Internal MicroSD slot

HPE specifies the MicroSD slot as non-hot-pluggable.

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Operating System Support

The ML110 Gen10 platform supports operating environments including:

• Microsoft Windows Server
• Red Hat Enterprise Linux (RHEL)
• SUSE Linux Enterprise Server (SLES)
• VMware
• ClearOS

HPE also documents community support for certain CentOS versions in the applicable QuickSpecs.

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Ideal Applications

The HPE ProLiant ML110 Gen10 4LFF Hot Plug CTO Server is suitable for:

• Small and medium businesses
• File servers
• Application servers
• Database workloads
• Backup servers
• Storage servers
• Branch-office infrastructure
• Remote-office environments
• Virtualization
• Business applications
• General-purpose server workloads
• Network services

The 4LFF hot-plug configuration is particularly useful for customers who prefer 3.5-inch high-capacity HDDs or SSDs and want the ability to replace supported drives without powering down the server.

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Why Choose the HPE ML110 Gen10 872307-B21?

The 872307-B21 provides a flexible foundation for building a customized HPE Gen10 server.

Key Advantages

• 4.5U tower form factor
• Single Intel Xeon Scalable processor
• 6 DDR4 RDIMM slots
• Up to 192GB RDIMM memory
• 4 × LFF Hot Plug bays
• Upgradeable to 8 LFF with appropriate configuration
• Embedded HPE Ethernet 332i 2-port 1GbE
• 5 × PCIe 3.0 slots
• HPE Smart Array RAID options
• HPE iLO 5 remote management
• Intelligent Provisioning
• Multiple power-supply options
• Excellent flexibility for SMB and enterprise ROBO environments
  

  Specification	Details
  Brand	HPE
  Product Family	ProLiant
  Model	ML110 Gen10
  Part Number	872307-B21
  Server Type	Tower Server
  Form Factor	4.5U Tower
  Configuration	Configure-to-Order (CTO)
  Processor Sockets	1
  Processor	Not Included – Configurable
  Chipset	Intel C621
  Memory Type	DDR4 Registered DIMM (RDIMM)
  DIMM Slots	6
  Maximum Memory	Up to 192GB RDIMM
  Drive Bays	4 × LFF Hot Plug
  Drive Form Factor	3.5-inch
  Hard Drives	Not Included – Configurable
  Storage Controller	HPE Smart Array S100i SR Gen10 / Optional Smart Array
  RAID	RAID 0, 1, 5, 10 via S100i for supported SATA configurations
  Network	Embedded 2-Port 1GbE HPE Ethernet 332i
  PCIe	5 × PCIe 3.0
  Management	HPE iLO 5 with Intelligent Provisioning
  USB	Front, rear and internal USB ports
  Power Supply	350W / 550W ATX or optional 500W/800W Flex Slot options
  Condition	Refurbished
  Warranty	1 Year